Abstract

Provided are methods for treatment of bladder cancer using compositions of modified Mycobacterium bovis Bacillus Calmette et Guerin (BCG). Also, provided are methods of treatment of non-muscle invasive bladder cancer by intra-bladder injection of these modified BCG compositions. Also, provided are methods of treatment of muscle-invasive bladder cancer by intra-tumor injection of these modified BCG compositions.

Application Number

PCT/US2020/056381

Date of Application

October 19, 2020

Inventors

Russell Ault, Niannian Ji, Juan I. Moliva, Robert Svatek, and Jordi B. Torrelles