We are looking for a talented, highly motivated postdoctoral researcher to join the laboratory of Dr. Melanie Carless to study the genetic and epigenetic contributions to complex diseases and establish related translational models. Our laboratory focuses on complex diseases, such as cardiometabolic and psychiatric diseases, which are associated with high mortality and morbidity rates. The primary project will incorporate next-generation sequencing, stem cell culture, and epigenetic editing technologies to investigate the role of DNA methylation in obesity and related phenotypes. Additional ongoing projects in the laboratory incorporate similar technologies to better understand the role of microRNAs in neuropsychiatric disorders and to establish potential mechanisms of treatment using human and non-human primate animal models. The successful applicant will join a dynamic research program aimed at defining causal epigenetic signatures of chronic complex diseases and developing therapies aimed at combatting these. The applicant will report to Dr. Melanie Carless, and will be expected to conduct laboratory-based research as well as prepare and publish scientific manuscripts. They will be trained in experimental techniques and scientific communication, and mentorship will be provided for career advancement.
EDUCATION/EXPERIENCE/SKILLS: Required: PhD in genetics, biomedicine, molecular biology, neuroscience, or related discipline. Substantial experience with cell culture techniques. Good oral and written communication skills. Preferred: Experience in stem cell reprogramming, maintenance and/or differentiation. Experience with gene-editing tools, molecular biology, fluorescence imaging and analysis, nucleic acid and protein extraction, next-generation sequencing, bioinformatics, and/or animal models is desirable but not mandatory.
POTENTIAL HAZARDS: This work may involve potential exposure to carcinogens, toxic materials, other hazardous chemicals, cryogenics, UV light, microwave, and infectious materials (BSL-2). Participation in a medical monitoring and surveillance program is required. Safety training, equipment, clothing and supplies will be provided.
OTHER: This is a full-time salaried (exempt) position. Texas Biomed business hours are Mondays through Fridays 8:00 a.m. to 5:00 p.m. Texas Biomed is committed to a drug-free workplace. Pre-employment drug screen is required.
Application packets are accepted electronically or in hard copy. A completed application packet is a requirement for all positions. Incomplete applications will not be accepted. Equal Employment Opportunity/M/F/Disability/Protected Veteran Status
Your resume and application must be provided electronically. Please follow the steps below.
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