On December 6, 2017, the Founder’s Council presented $75,000 in grants to the following Texas Biomed researchers to buy equipment in support of their work:
Dr. Tim Anderson, Dr. Ian Cheeseman, Dr. Ashish Kumar, Dr. Smita Kulkarni, Dr. Shelley Cole
Compute server and RAID storage for Genomics Sequencing Core Facility – DNA/RNA sequencing is a key component of many biomedical investigations and central to our
research in areas such as malaria, schistosomiasis, neuropsychiatric disease, malaria, HIV and Crohn’s disease.
Dr. Winka Le Clec’h and Dr. Frédéric Chevalier
Nikon Stereomicroscope with Diascopic Illumination Stand – This microscope will be used to research Schistosomes. Schistosomes are parasites that infect over 200 million people in 77 countries worldwide. They rank second behind malaria in terms of mortality.
Dr. Melanie A. Carless
Inverted Ts2 microscope LED fluorescence upgrade package – This will allow us to track genetic changes in cells and will be used as we study mental and neurological diseases such as Bipolar disorder, depression, Alzheimer’s and Parkinson’s disease.
Dr. Eusondia Arnett
NanoDrop One C – The NanoDrop One C is a highly sensitive spectrophotometer, which measures absorbance readings and calculates DNA, RNA, and protein concentrations. This is a critical piece of equipment for anyone doing molecular biology work and will be used in our Tuberculosis lab.
Dr. Pat Frost, Veterinary Resources
Edan Interpretive EKG – The fields of research that an EKG can be applied to has a wide breadth. Some examples of these are surgical protocols, pharmacokinetic studies, infectious disease experiments, cardiovascular model development (stroke, cardiac interventional studies), chagas and other applications yet to be identified.
Dr. Elizabeth Clemmons
Ophthalmoscope/otoscope unit – This equipment will be used for nonhuman primate eye and ear exams. The ophthalmoscope portion of this unit allows examination of the cornea, iris, vitreous humor, retina and optic disc. A variety of issues that are studied at TBRI can affect the eye including neurologic disorders, metabolic disease, aging, HIV and other infectious diseases.
Dr. Kathleen Brasky
Accuvein AV400 – A device for blood sampling or intravenous administration. It will be used to evaluate HIV vaccines or therapeutics, and evaluating therapies for obesity, aging, Parkinson’s disease and whooping cough.
Dr. John “Jack” Dutton, DVM
Matrix Anesthetic System – A few examples of research projects that will be greatly aided include hemorrhage studies and many other surgical procedures.
Dr. Elda Mendoza
Anesthesia Monitor – Many of our research study procedures will benefit with using this device. It will be used in monitoring non-human primates heart rate, respiration rate, and blood pressure while under anesthesia.
Dr. Edward J. Dick
HemataSTAT II Centrifuge – This equipment will be placed in the central clinical pathology laboratory where it will be used in support of all research projects that require analysis of hematocrit (a basic and usual assay in almost all blood sample analysis).
Dr. Tiziano Barberi
EVOS LED Cube/RFP – This equipment will be used in many research projects, one in particular aimed at restoring skeletal muscle function in muscular dystrophy. A study with a high potential for future clinical relevance.
Dr. Christopher Chen
QIAcube – This machine will automate the isolation and purification of RNA and DNA from cells and tissues.
Dr. Beata Boczkowska
Mastercycler Nexus Gradient thermal cycler Nexus grad – This instrument allows for fast optimization of protocols used for the detection of minute amounts of viral DNA in a wide variety of samples. It will be used to optimize protocols for the detection of Ebola.
Dr. Marie-Claire Gauduin
EPIFluorescence upgrade for microscope – This equipment will be used to help develop an effective genetic vaccine to fight the AIDS virus.
Dr. Olena Shtanko
Eppendorf ThermoStatTM C – this will be used to study how highly pathogenic viruses, such as Ebola and Crimean-Congo hemorrhagic fever viruses, find their way into cells. The studies need to be performed in the BSL-4 laboratory, and experiments require a device that allows safe, precise, and fast heating and cooling steps, ideally suited for these experiments.
Dr. Patricia Carlisle
Magnetic Plate Separator – we can study the presence of antibody against particular Ebola virus proteins and even pinpoint the parts of these proteins responsible for the strongest immune response. Knowing these epitopes will greatly advance the search for vaccine candidates and treatments protecting against Ebola.
Yenny GoezGazi, DVM
DynaMag2 Magnet – With this state of the art technology, it will allow us to screen a large number of samples while obtaining detail measurements of intensity and quality of immune response. Specifically, we can study the presence of antibody against particular Ebola virus proteins.
Dr. Michal Gazi
HulaMixer® Sample Mixer – This equipment has broad use in the laboratory, but it will be mainly used during preparation of magnetic beads coated with peptides and antibodies. These beads are then used for analysis of sera associated with the Ebola virus.
Dr. Andrew Hayhurst
Superdex 200 gel filtration column – this equipment will play a pivotal role in allowing us to generate high-quality proteins that generate high-quality data to study the current outbreak of the Marburg Virus in Uganda. This virus is transmissible and is a highly lethal pathogen.