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Compositions And Methods Of Controlling Expression Of Thermogenin (UCP-1) In Skeletal Muscles

Abstract

Described herein are pharmaceutical compositions containing genes encoding a positive regulatory domain zinc finger protein 16, a peroxisome proliferator-activated receptor gamma coactivator 1-alpha protein, and a bone morphogenetic protein 7. Also disclosed are methods of treating or managing obesity and diabetes by delivering these pharmaceutical compositions using ultrasound-targeted microbubble destruction.

Application Number

16/502,509.

Date of Application

7/3/2019.

Inventors

Raul Bastarrachea.