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Single Domain Antibodies Reactive To Ebolaviral Nucleoprotein

Abstract

Isolated antibodies that bind to a nucleoprotein or a portion thereof of a plurality of ebolaviral species, such as Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV), Bundibugyo ebolavirus (BDBV), Taï Forest ebolavirus (TAFV), Reston ebolavirus (RESTV), Bombali ebolavirus (BOMV), are provided. Compositions comprising the antibodies and immunoassay methods for detecting the presence or amount of an ebolaviral nucleoprotein or a portion thereof using the antibodies are also provided.

Application Number

63/478,478 (provisional)

Date of Application

January 4, 2023

Inventors

Andrew Hayhurst and Laura Jo Sherwood