New COVID-19 Research Projects at Texas Biomed

  • Point of Care Diagnostic Development for SARS- CoV-2

    One of the biggest issues in the outbreak is identifying how many people are infected,which would provided details on where the virus is emerging and a true fatality rate. Point-of Care diagnostics are needed for diagnosis without having to send samples out.Texas Biomed scientists have two projects with UCSC and UCSF one in nanopore-based multi-target analysis and a new CRISPR diagnostic test of SARS-CoV-2.

  • Development of a baboon model of SARS-CoV-2 infection

    Scientists aim to demonstrate that the baboon can serve as a validated animal model for consistent infection with SARS-CoV-2. The availability of a valid NHP model of SARS-CoV-2 infection will facilitate studies related to diagnosis, pathogenesis and transmission, as well as pre-clinical testing of vaccines and therapeutics against this virus

  • Isolation and characterization of COVID-19 spike(S)-specific broadly neutralizing human monoclonal antibodies(BNhMAbs)

    Scientists expect to identify several COVID-19 S protein binding hMAbs, which will have therapeutic and prophylactic activity against COVID-19 infection in vivo for the implementation as effective immunotherapeutics against COVID-19 infections in humans

  • Generation of LAV for the treatment of COVID-19 infections

    Scientists aim to successfully identify an attenuated form of COVID-19 for employment as a Live-Attenuated Vaccine, which is urgently needed for prevention of COVID-19 infections

  • Development of reverse genetics(RG) systems for COVID-19

    Scientists aim to facilitate the study of COVID-19 infections, including the identification of antivirals and neutralizing antibodies for the treatment of COVID-19 infections